First insights into health issues related to blooms of the cyanobacterium Lyngbya cf. majuscula in New Caledonia

Olivier P. Thomas , Hiren Solanki , Mayalen Zubia (1) , Sandra Gegunde , Kevin Calabro , Georges Kakue , Amparo Alonso-Betanzos , Luis M Botana , Claude Payri (2)

1 EIO - Ecosystèmes Insulaires Océaniens (UMR 241)
2 ENTROPIE [Nouvelle-Calédonie] - Ecologie marine tropicale des océans Pacifique et Indien

Cyanobacterial blooms are becoming more recurrent in the Pacific Ocean leading to health but also economic concerns among the local communities. Recently, closures of beaches have resulted from the yearly occurrence of blooms of a cyanobacterium related to Lyngbya majuscula. The project CYCLADES was recently supported by the Pacific Fund to give some insights into recent events of dermatitis associated with these blooms in the Drehu island of New Caledonia. We report the first results on the chemical diversity identified in specimens overgrowing corals in the affected beach. New linear and cyclic modified peptides were isolated as major metabolites together with the known dolastatin 3. Additionally, some modified fatty acids are reported for the first time and all metabolites were biologically tested.

Domains: Life Sciences [q-bio]

Olivier P. Thomas, Hiren Solanki, Mayalen Zubia, Sandra Gegunde, Kevin Calabro, et al.. First insights into health issues related to blooms of the cyanobacterium Lyngbya cf. majuscula in New Caledonia. XVI International Symposium on Marine Natural Products, Sep 2019, Peniche, Portugal. ⟨hal-03211616⟩